The global oligonucleotide synthesis market is expected to witness significant
demand over the forecast period. Oligonucleotides are short nucleic acid
polymers used in research, genetic testing and forensics. Oligonucleotides are
usually made up of 13 to 25 nucleotides and are designed to hybridize specifically
to DNA or RNA sequences. Solid-phase clinical synthesis is used to manufacture
these small bits of nucleic acid for use in polymerase chain reaction (PCR),
DNA sequencing, library construction and artificial gene synthesis.
Oligonucleotide synthesis is the chemical synthesis of
relatively short fragments of nucleic acids with defined chemical
structure/sequence.In the enzymatic process of DNA synthesis,
deoxy-ribonucleotide-5-tri-phosphates are used as substrates during
polymerization. In addition, this process requires a primer and a template.
The most frequently used oligonucleotide synthesis strategy
is based upon beta-cyanoethylphosphoramidite chemistry. The synthesis proceeds
from the 3’ to the 5’ end of the oligonucleotide, which is in opposition to the
enzymatically catalyzed reaction where polymerization proceeds from 5’- 3’. The
synthesis continues repeating cycle until the sequence of the oligonucleotide
has been built.
Browse Full Research
Report @ https://www.millioninsights.com/industry-reports/oligonucleotide-synthesis-market
Growing R&D spending in pharmaceutical and biotechnology
companies, increased use in clinical applications and molecular diagnostics,
growing government investments for the development of genomics and
developingconsequence of RNA-interference oligos in the therapeutics and
diagnostics are the key factors driving market size for oligonucleotide
synthesis.
Whereas, high cost of synthesized oligonucleotides and strict
regulatory requirements for the approval of oligonucleotide-based therapeutics
are some of the factors constraining the growth of the oligonucleotide
synthesis market to some extent.
On the basis of product type and services, the
oligonucleotide synthesis market is classified into by Product (Synthesized
Oligonucleotides, Primers, Probes, Intermediate-scale synthesis Oligos,
Large-scale synthesis Oligos, Linkers and Adaptors), By Services (Custom
Oligos, Pre-designed Oligos, Reagents, Equipment).Synthesized oligonucleotides
segment is expected to account for the largest market share in the forecast
period. This is due to the increasing number of applications of synthesized
oligonucleotides in research, diagnostics, and therapeutics. The mounting
demand for custom oligos also subsidizes to the growth of the synthesized
oligonucleotides market.
On the basis of application, the oligonucleotide market is
classified into Research, Diagnostics, Therapeutics. Research segment is
sub-segmented into PCR, qPCR, DNA Sequencing, Gene Synthesis, other.
Therapeutics is further sub-segmented into DNA/Antisense oligo’s, RNA, Nucleic
acid aptamers, Immunotherapy Applications.
Research segment accounts for the largest market size of
oligonucleotide synthesis market. Diagnostic segment is likely to grow at
highest CAGR during the forecast period. This is mainly due to the developing
application of molecular diagnostics (MDx) and genetic testing. The growing use
of technologies such as DNA microarrays in the analysis of biological samples
and developing molecular oncology diagnostics tests also subsidize in the
growth of molecular diagnostics market size.
Request Sample Copy of
this Market Research @ https://www.millioninsights.com/industry-reports/oligonucleotide-synthesis-market/request-sample
Comments
Post a Comment